In type 1 diabetes (juvenile diabetes) is an autoimmune condition in which the pancreas fails to produce insulin, a hormone needed for glucose to enter cells. Insulin administration maintains blood glucose control for people with type 1 diabetes. In type 2 diabetes (diabetes mellitus) insulin is produced yet not assimilated properly, leading to insulin resistance. The American Diabetes Association describes type 2 diabetes as the most common type of diabetes. Adhering to a diet plan and exercising may be sufficient for some individuals, while others require diabetic medications or insulin therapy. Your physician will determine suitable treatment options based on your lifestyle and health needs.

The New England Journal of Medicine reports in their article, Saxagliptin and Cardiovascular Outcomes in Patients with Type 2 Diabetes, reports a randomized study on the effects of Onglyza (Saxagliptin) in diabetic patients with a history of established vascular disease. The study was conducted over a period of 2 years in 16,500 Type 2 diabetic patients from 26 countries.