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Clients with Rheumatoid Arthritis (RA) unresponsive to Disease-Modifying Medications (DMARDs) and other commonly prescribed drugs may benefit from biologic response modifiers or biologics. Biologic agents are drug therapies for clients with moderate to severe Arthritis. Unlike traditional RA medications, biologics target specific areas in the immune system decreasing inflammatory response and joint pain. Biologics can be administered alone or in combination with other pharmaceuticals. WebMD comments on biologic therapy stating, “Biologics are genetically-engineered proteins derived from human genes. They are designed to inhibit specific components of the immune system that play pivotal roles in fueling inflammation, which is a central feature of rheumatoid arthritis.” Biologics have been a breakthrough in managing RA for clients who have seen little if any improvement with traditional drug therapies.

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in Medicine 1051
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Arthritis is inflammation of the joints commonly presenting as joint stiffness, pain, and tenderness. Arthritis can exacerbate during climate changes particularly in cold winters and hot summer days. The Arthritis Foundation references a clinical study on climate temperature and joint pain, “In 2007, researchers at Tufts University in Boston reported that every 10-degree drop in temperature corresponded with an incremental increase in arthritis pain. Increasing barometric pressure was also a pain trigger in the Tufts study.” Climate changes can result in arthritis flares presenting sudden pain and inflammation. Managing arthritis extends beyond pharmacological agents. Pain medications and anti-inflammatory agents are often prescribed to manage symptoms, yet many carry potential side effects. With the guidance of healthcare professionals clients can also benefit from natural therapies.

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in Wellness 1361
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